SOX9 GOVERNS DIFFERENTIATION STAGE-SPECIFIC GENE EXPRESSION IN GROWTH PLATE CHONDROCYTES VIA DIRECT CONCOMITANT TRANSACTIVATION AND REPRESSION.

SOX9 governs differentiation stage-specific gene expression in growth plate chondrocytes via direct concomitant transactivation and repression.

Cartilage and endochondral bone development require SOX9 activity to regulate chondrogenesis, chondrocyte proliferation, and transition to a non-mitotic hypertrophic state.The restricted and reciprocal expression of the Cakes collagen X gene, Col10a1, in hypertrophic chondrocytes and Sox9 in immature chondrocytes epitomise the precise spatiotempora

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Determinants of journal choice among Nigerian medics

INTRODUCTION: despite the well-known maxim "publish or perish" among academicians, productivity remains low in Nigeria.There are barriers to academic writing which must be identified and addressed.Even after dressing those barriers, authors are faced with another dilemma-where to publish.It was the concern of the authors to evaluate perceived barri

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Contemporary Britain in the Works of Russian Scholars

The article is dedicated to major findings of Russian scholars on a broad range of topics in the field of British studies.The works selected are mainly 30" True Convection Wall Oven focused on the analysis of political, security and socio-economic models of development and trends in the UK from 1991 to 2021.The topics, which were most elaborated in

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